RAQ is BAQ! The Burlington-native jam-rock quartet has announced a very special weekend run, going down September 14th and 15th at Denver, Colorado’s Be On Key Psychedelic Ripple. For the run, the band, comprised of keyboardist Todd Stoops, bassist Jay Burwick, and guitarist Chris Michetti, will be joined by drummer Jay Lane before he heads out on tour with Bob Weir and Wolf Bros. For these two performances with Jay Lane, RAQ will temporarily call itself RAQ+ (pronounced “RAQ Plus”) in his honor, as they have done two previous times in the past.For this two-night run, RAQ+ will also be joined by Fellowship of the Wing, with Jay Lane and Todd Stoops pulling double duty and joining guitarist John Kadlecik and bassist Reed Mathis in the Golden Gate Wingmen spin-off. For tickets to see RAQ+ and Fellowship of the Wing, head to Be On Key’s Psychedelic Ripple’s website here.
On Monday, December 31st, KNOWER (full-band) and Ghost-Note (featuring MonoNeon, Robert “Sput” Searight, Nate Werth, and more) will close out 2018 together with a special New Year’s Eve performance at New York City’s Irving Plaza. While distinctly different in sound and style, both bands bring a level of “weird” that will make for an exciting night of music. For ticketing information, head here.It’s time to get on the KNOWER train if you aren’t already on it. The Los Angeles-based group led by Louis Cole and Genevieve Artadi is currently spearheading a new musical movement and is known for their use of hard-hitting funk, cool chords, and deep melodies. Another career started on the Internet—specifically YouTube—the “indietronica” duo was featured on Snarky Puppy‘s Family Dinner Vol. 2 in 2015, expanded to a five-person live act in 2016, opened for the Red Hot Chili Peppers in four major European cities in 2017, and played Colorado’s Red Rocks Amphitheatre with Vulfpeck and Kamasi Washington in April of this year.An entirely do-it-yourself act since their formation in 2010, KNOWER’s viral videos, discography, and live visual experience have become an international internet phenomenon. Clocking millions of views, their live “band house sesh” hit over 3.5 million views in just one week. Known for their live shows, they take their infectious energy to another level. Quincy Jones best sums up why you can’t miss them, “KNOWER WILL BE LEAVIN’ YA’LL ON YOUR KNEES, BEGGIN’ FOR MORE.” Positioned for enormous success in 2019, KNOWER is a band/sound/feeling that can’t be stopped.Knower – “Time Traveler” (Live Band Sesh) – 2017Ghost-Note, the musical brainchild of multi-Grammy Award-winning Snarky Puppy percussionists Robert “Sput” Searight and Nate Werth, is comprised of Dywane “MonoNeon” Thomas Jr. (bass), Xavier Taplin (keys), Vaughn “V-Keys” Henry (keys), Peter Knudsen (guitar) and Jonathan Mones (alto sax & flute).After launching their debut record, Fortified, in 2015 to showcase the diverse musical landscape of Dallas, TX, Searight and Werth found their identity in the Ghost-Note moniker. This past spring, the pair headed back into the studio for the follow-up release, Swagism, which garnered a #1 position on the iTunes jazz charts.Swagism showcases an evolved sound, elaborating on the sonically powerful and diverse talents of each individual member of the group. It features over 20 guest musicians, including Kamasi Washington, Karl Denson, Nigel Hall, Brandon “TAZ” Niederauer, and many more. Listen to Ghost-Note’s Swagism below:Ghost-Note – Swagism – Full AlbumLive performances by both KNOWER and Ghost-Note have been somewhat scarce, until now. As such, this is a billing you won’t want to miss! With so much diverse talent on one stage, there’s no telling what will go down. And what better way is there to spend New Year’s Eve than with pure musical mystery? For ticketing information, head here.
Read Full Story New research led by Harvard T.H. Chan School of Public Health has identified numerous genes that influence how cells respond to saturated fatty acids. Some of these genes have promise as potential therapeutic targets for treating metabolic diseases associated with lipotoxicity, including obesity, diabetes, and heart failure.The study also provides new insights into how saturated fatty acids trigger cellular stress and showed that saturated fatty acids are less toxic to cells when they are combined with unsaturated fatty acids.“This study, which analyzes all genes in the human genome, provides a wealth of new information for how saturated fats harm cells. It not only sheds light on the biology but also identifies a number of new targets for possible therapies,” said corresponding author Robert Farese Jr., chair of the Department of Genetics and Complex Diseases at Harvard Chan School.The study was published in Molecular Cell. The findings were reported from the laboratory of Farese and Tobias Walther, who study lipid metabolism in a joint laboratory.Saturated fatty acids, which are found in foods such as red meat, cheese, and butter, are generally considered bad for health and can raise levels of “bad” LDL cholesterol. When consumed, saturated fatty acids are processed in many different ways. They can be used by cells as building blocks for membrane lipids, stored in lipid droplets, or used to modify proteins. While it’s known that the accumulation of saturated fatty acids can lead to cell and tissue “lipotoxicity,” a metabolic syndrome that is associated with various diseases including diabetes and obesity, very little is known about the various cellular pathways involved in mediating and modifying the toxic effects of saturated fatty acids.In this study researchers exposed human cells to the saturated fatty acid palmitate, which is found in palm oil. They then examined how this exposure affected a cell’s RNA and its lipids, as well as the genetic interactions that occurred in response to palmitate.The study revealed that when saturated fatty acids flow unchecked into complex lipids within cells, they causes massive stress that can ultimately kill the cell. However, when saturated fatty acids were prevented from being incorporated into these complex lipids, cell death was prevented. For example, the researchers found that the enzyme GPAT4 plays a critical role in regulating lipotoxicity. They discovered that blocking the enzyme prevents the entry of saturated fatty acids into biosynthetic pathways within the cell, which in turn alleviates stress and cell death normally caused by saturated fats.Using genome-wide screening technology, the authors also identified dozens of genes that can protect a cell from or sensitize a cell to the detrimental effects of palmitate. In doing so, the study highlighted several unexpected pathways that could potentially serve as new therapeutic targets for diseases associated with lipotoxicity. Among the potential targets is the gene RNF213. The researchers said they were surprised to discover that RNF213, which had not previously been implicated in lipid maintenance before, acts as an important regulator of lipotoxicity.
MINNEAPOLIS (AP) — Gov Tim Walz has authorized the Minnesota National Guard to deploy in preparation for potential civil unrest during the upcoming trials of four ex-Minneapolis police officers charged in the killing of George Floyd last summer. The Democratic governor’s executive order authorizes the deployment of an unspecified number of troops in Minneapolis and St. Paul. They would serve during both the trial of ex-officer Derek Chauvin, which is scheduled to begin March 8, and three other former officers scheduled for trial in August. Authorities have been preparing for months, fearing a repeat of violence that erupted after Floyd’s death last May.
Courtney Becker | The Observer A student calls his representatives Wednesday to advocate for immigration awareness in response to President Donald Trump’s decision Tuesday to rescind the DACA program, effective in six months.According to a DACA fact sheet SCIA gave those who attended the call-in, DACA is a Department of Homeland Security policy signed into effect by former President Barack Obama, and it allows certain undocumented immigrants under 30 years old who are either enrolled in or have graduated from school without a felony conviction to delay their deportation for two years at a time and obtain a work permit. DACA recipients were brought into the United States as children, pay federal taxes and are not allowed to vote or receive federal benefits.Junior and DACA beneficiary Kevin Perez, the marketing director of SCIA, said it is heartening for him and other DACA students at Notre Dame to see support for the DACA community.“It means a lot. We’ve already had over 100 people in the first hour,” Perez said. “And it’s good to know that we have this support from our fellow classmates because some of us are in this situation — me, personally, I have DACA — and it’s just very encouraging to see students and faculty coming out.”Junior and DACA beneficiary Gargi Purohit, the president of SCIA, said the call-in was a chance for allies to “put their words into action.”“It’s a great way to see people actually taking action, because so many of us have said, you know, they support us and that they’re here for us, but we also need people to put their words into action,” Purohit said. “So it’s coming out to these events and calling representatives. And also, it’s great to see people continue to have interest in it. So we’re giving them other resources and tools to continue to do this by themselves as well.”Rescinding DACA would be problematic, junior Jackson Hignite said, because several DACA beneficiaries can’t remember living anywhere other than the U.S.“DACA is an important program,” he said. “Even if it’s not an executive program you’ve gotta, in some way, protect the 800,000 kids that came here — some legally, some illegally — that are documented through this program, who don’t know any other country besides America.”Sophomore Amber Grimmer said the call-in was important not only in terms of reaching out to representatives, but also creating a conversation about DACA on campus.“This is all in the spirit of democracy,” she said. “First of all, just the solidarity — I’m incredibly thankful for everyone just showing up to support the students at our school. That means a lot to be in solidarity. And also [we want] to create discussions. Because now everyone is talking about it in this room and maybe in other places, too.”Purohit encouraged all DACA allies to consider the entire undocumented community in their advocacy.“A lot of allies, when they’re talking about DACA, at times they will demonize our parents and I think that’s just the completely wrong message,” she said. “ … Not to mention, not all dreamers came here illegally. I came here legally — I think through LaGuardia — on a visa with my mom, so there’s just a lot of things that people need to keep in mind when they’re using their language.”Those affected by the Trump administration’s announcement may also still be processing the information, Purohit said.“Honestly, I didn’t really have time to process my feelings yesterday because I was so busy running this that I still don’t think it has completely hit me yet on the severity of this decision,” she said. “I’m trying to run around and make sure that we get something done before something really awful happens, like some dreamers get deported. So I’m still kind of in a bit of shock.”After University President Fr. John Jenkins released a statement Tuesday vowing to support DACA students at Notre Dame, discernment and advocacy director at the Center for Social Concerns Mike Hebbeler said it was the kind of Catholic leadership needed at the moment.“For Fr. Jenkins to make that statement, that demonstrates that commitment to leadership rooted in gospel values and Catholic social tradition that animates our campus community and extends into our local South Bend community,” Hebbeler said.The easiest way for people to get involved and fight for DACA recipients, Perez said, is to educate themselves about the program.“We don’t really know what the future holds at this point, but the first thing is just awareness,” Perez said. “Just letting people on campus know that there are students like us here and kind of educating them about immigration law programs like DACA. Because I think a lot of people on this campus don’t really know what it is or think they do but don’t know all the facts or details about it.”Hebbeler said he would encourage people to not only educate themselves about what DACA is, but also to try to get to know one of the community members with DACA status.“My response to people who are unfamiliar with it, or may be apathetic about it or who even oppose it, is to get out into the community or, on campus, find a way to connect to people who are directly affected by it and meet them,” Hebbeler said. “And in that relationship building, there can arise an understanding of a shared humanity … and in that encounter, I think, not only can minds be informed, but hearts can be changed.”Tags: DACA, Donald Trump, Student Coalition for Immigration Advocacy Notre Dame students, faculty and other community members rallied around those at the University affected by Tuesday’s announcement that President Donald Trump will phase out Deferred Action for Childhood Arrivals (DACA) in six months’ time by contacting representatives around the country at a call-in Wednesday.The Student Coalition for Immigration Advocacy (SCIA) hosted the call-in to support undocumented immigrants and used it as an opportunity to educate the Notre Dame community about DACA, which affects over 800,000 undocumented immigrants in the U.S.
Runjie Pan | The Observer Dr. Carol Anderson speaks as part of the Race and Ideas Lecture Series Wednesday. Her talk, “White Rage: The Unspoken Truth of our Nation’s Divide” focused on resistance to racial progress in America.“White rage is not about the way we often think about racism,“ Anderson said. “White rage is not overtly violent. It’s not a [Ku Klux] Klan cross burning. White rage works smoothly, calmly, efficiently, through the legislature, through the courts, through the White House, through Congress, through school boards, through zoning commissions. It works subtly, it works corrosively. And I also began to realize that for white rage to become operational, it wasn’t the presence of black people that did it … Black advancement is the trigger for white rage.”While the seed of Anderson’s understanding of white rage was planted by the 1999 shooting of Amadou Diallo, an unarmed, 23-year-old black man, by four New York City police officers, it was not until the protests in Ferguson, Missouri, following the death of Michael Brown that her ideas fully formed. Part of it comes from the narrative of black pathology.“It didn’t matter if it was MSNBC, CNN, or Fox. It didn’t matter. They were all saying the same thing: look at black people burning up where they live … because when you begin to think about it, underneath all of that is a key element that lives vibrantly in American society,“ Anderson said. ”And that is the narrative of black pathology, that there is something systemically wrong with black people.”Anderson said this perspective fails to consider the crippling of the African-American population through policy.“I saw the way that African-Americans’ rights were systematically undermined, but what I also saw, being in this nation, is that we are so focused in on the flames that we miss the kindling. We see the fire and we don’t see what started that fire. And that fire, that kindling, are the policies,” she said.Anderson went on to describe that “kindling,” from policing strategies and voter ID laws to apathetic school boards and mass incarceration. Many of the policies that disenfranchise the African-American population, Anderson said, are couched in patriotic terms that are difficult to argue with. One such instance is the War on Drugs, which many studies show disproportionately targeted African-Americans, Anderson said.“What the War on Drugs actually does is that it eviscerates the Civil Rights Act of 1964 … The rights that are protected under the Civil Rights Act do not apply to felons. So if you have mass incarceration of African-Americans, you have just reversed the gains of the Civil Rights Act of 1964. And, as an added bonus, you have permanent felony disenfranchisement, which means that if you have a felony conviction, you cannot vote,” Anderson said.Anderson pointed to the recent focus on voter identification laws following the 2008 election and the subsequent state policy changes that make it virtually impossible for many African-Americans and other minorities to obtain the appropriate identification. In reality, voter fraud is an incredibly rare occurrence, according to a study conducted by Justin Levitt of Loyola Law School in Los Angeles.“He looked at voter impersonation fraud because this is what voter ID laws go after … he looked, and what he found, from the years 2000 to 2014 or 15, out of one billion votes there were 31 cases. Yet we have 33 states that have implemented voter suppression laws using the language of protecting the integrity of the ballot box,” Anderson said.Anderson then traced the history of white rage, linking every gain for the rights of African-Americans to a massive pushback from white supremacy embedded in governmental institutions. Anderson finished with a reading from her book, calling for honest conversation and a refusal to stand by and allow oppression to continue.“Not even a full month after Dylann Roof gunned down nine African-Americans at Emmanuel AME, Republican presidential front runner Donald Trump fired up an audience of thousands in July 2015 with a macabre promise: ‘Don’t worry, we’ll take our country back.’ No. It’s time, instead, that we take our country forward, into the future. A better future,” Anderson said.Tags: Africana Studies, Barack Obama, Donald Trump, Dr. Carol Anderson, Race and Ideas Following the backlash against a lecture given by political scientist Charles Murray last spring, the department of Africana Studies initiated the Race and Ideas Lecture Series in partnership with several other academic departments. The second speaker in that series, Dr. Carol Anderson of Emory University spoke on Wednesday night about her most recent book, “White Rage: The Unspoken Truth of Our Nation’s Divide.”Anderson explained that racism does not always manifest itself in expected ways.
Show Closed This production ended its run on June 19, 2016 Frank Langella in ‘The Father'(Photo: Joan Marcus) View Comments Theatergoers enter Broadway houses to have their hearts broken and filled, and Florian Zeller’s The Father beautifully delivers on both fronts.Three-time Tony winner Frank Langella’s welcome return to the Great White Way is sure to delight those who witnessed his work in Frost/Nixon, Fortune’s Fool and Seascape (and perhaps more so, those who have not yet had the privilege of seeing him in action). At the same time, this Doug Hughes-helmed production devastates, zeroing in on the life of Andre (Langella), a retired tap dancer (or was he an engineer?) whose experience with dementia captures the very human fear of mortality.”We’re all going to die, and we’re all worried about being out of control,” Langella told Broadway.com at the play’s Manhattan Theatre Club opening on April 14. “Those are universal themes in human beings, and certainly, when you get to be up in my years, so many friends around you are suffering with this disease or thinking about mortality. The play addresses it, but it addresses it in such an extraordinary way.”Translated by two-time Tony and Oscar winner Christopher Hampton, Zeller’s Molière Award-winning drama is a brutally honest examination of disease and its effects on those who witness its unraveling of the human spirit (in this play’s case, Tony nominee Kathryn Erbe, Charles Borland, Kathleen McNenny, Hannah Cabell and Brian Avers).No matter one’s age or relationship to dementia, The Father’s lesson is absolutely essential. As Langella beautifully and heart-breakingly put it, “I suppose the greatest thing you could take away from it is not to waste a minute of your life.”The limited engagement is currently running at the Samuel J. Friedman Theatre through June 12 and is not to be missed.Additional reporting by Imogen Lloyd Webber. Related Shows Frank Langella The Father Star Files
During some University of Georgia research on a newinsecticide to control aphids on tobacco, scientists found a surprising side effect:hornworms on the plants turned white.”We thought there would be some effect on the worms because of the nature of thechemical,” said Robert McPherson,a UGA entomologist at the Coastal PlainExperiment Station in Tifton, Ga. “But we didn’t expect them to change color. Atall.” Scientists found the new insecticide, pyriproxyfen, did an “OK” jobcontrolling aphids, McPherson said. But the overall effect on the worms is moresignificant. It keeps them from changing from caterpillars into adults.The hornworm caterpillar stage lasts about three weeks. “And that’s long enough todo a lot of damage to plants,” McPherson said. In 1996, hornworms caused $2.6 millionworth of damage in tobacco. They also caused some damage in tomatoes.So waiting until the caterpillars pupate to die wasn’t fast enough for many farmers.They still saw the growing worms hungrily eating their tobacco and tomatoes.”But, what we’ve found is with white worms, the birds see them more easily andquickly pick them off the plants,” he said.That’s the fascinating part of the trial, McPherson said. “The hornworms the birdsdon’t get will die when they pupate,” he said.Later work in the lab showed the chemical binds to the chlorophyll in the plants.Chlorophyll is what gives the worms their green skin color. The bound chemicals preventedthe green from moving to the caterpillars’ skin. The worms turned white within two days ofthe insecticide application.Most worms that eat plants are really caterpillars. Caterpillars are young moths orbutterflies. They’ll grow for a while, eating just about every plant leaf they can, thenpupate. During their pupal stage, they mature into adult moths or butterflies.This new pesticide disrupts their life cycle. Normally, McPherson said, when the wormsbegin to pupate, their hormones cause them to mature into adults. “But the chemicalprevents that from happening. So they get stuck between juvenile and adult and die,”he said.”The good thing about this chemical is that it can’t affect any other insects thatmight be beneficial,” he said. “It works only on the worms’ hormones. It doesn’teven affect the birds that eat the hornworms.”The chemical does have similar effects on other types of worms, McPherson said.”Soybean loopers and velvet bean caterpillars both lose color and die during theirpupal stage,” he said. “So this insecticide may have some promise for the cropsthey eat, too.”During the 1997 tests, the first of the series, McPherson and the technicians who workwith him found that birds picked off nearly 40 percent of the worms before they began topupate. Though the worms lived about three days longer than normal, they still died beforethey could mature.”The generation that’s treated in the field does continue to cause damage,”he said. “But there isn’t another generation to feed on the plants and cause moredamage.” AN EASY TARGET FOR BIRDS’ BUFFET This now-white hornworm provides easy pickin’s for birds flying over the field. Hornworms, naturally green, rely on their coloring for camoflage protection from hungry birds. “This new chemical turns the worms white, making an easy meal for birds before it causes the worm to get stuck between its juvenile and adult stages and dies,” said Robert McPherson, a UGA entomologist. (Photo courtesy the UGA College of Agricultural and Environmental Sciences.)
Source: Union Bankshares. Morrisville, VT April 15, 2009 Union Bank,Union Bankshares, Inc. (NASDAQ UNB) has announced financial results for the first quarter ended March 31, 2009. The Company reported net Income of $1.27 million or $.28 per share compared to $1.41 million or $0.31 per share for the comparable period in 2008. The decrease in year over year net income is primarily due to increases in FDIC deposit insurance premiums of $123,000, pension plan expense of $145,000 reflecting a decline in the market value of pension plan assets under mark to market accounting and the receipt during the first quarter of 2008 of a $184,000 rehabilitation federal tax credit for one of the Company s low income housing partnership investments. These changes were partially offset by increased noninterest income during the first quarter of 2009, mainly due to the refinancing and sales of residential mortgages.Net interest income increased $21 thousand or 0.5%, which was less than anticipated, as a result of the 400 basis point decrease in the prime rate since January 1, 2008. The provision for loan losses for the first quarter of 2009 was $95 thousand compared to $50 thousand in the comparable period of 2008. The increase in the provision between years was mainly due to the $35.6 million, or 11.5%, increase in gross loans. Total loans, including loans held for sale, were $348.8 million at March 31, 2009 compared to $316.6 at March 31, 2008.Other operating expenses only increased $88 thousand or 2.3% between years despite the addition of two full service branches during the second half of 2008. The increase in other operating expenses was more than offset by the increase in other operating income of $158 thousand which is mainly due to the increase in income from the sale of residential mortgage loans.The Board of Directors, after careful consideration of the uncertainty in the current national economy, announcement by the Federal Deposit Insurance Corporation of a one-time additional deposit insurance assessment of $.20 per $100 of deposits as of June 30, 2009 (approximately $459,000 after tax), and the effects of mark to market accounting requirements, has determined that a decrease in the quarterly dividend is in the best interest of the Company at this time to maintain the Company s capital strength. On April 15, 2009 a quarterly cash dividend of $0.25 per share was declared to shareholders of record April 27, 2009, payable May 8, 2009. Dividend for the previous quarter was $0.28 per share.The Company under the Federal Reserve Board s regulatory capital standards is well capitalized with Tier 1 Capital to total assets at December 31, 2008 of 9.95%.Union Bankshares, Inc., with headquarters in Morrisville, Vermont is the bank holding company parent of Union Bank, which offers deposit, loan, trust and commercial banking services throughout northern Vermont and New Hampshire. As of March 31, 2009, the Company had approximately $421.8 million in consolidated assets compared to $388.2 million at March 31, 2008, or growth of 8.6%. The Company operates 14 banking offices and 29 ATM facilities in Vermont, a branch and ATM in Littleton, New Hampshire.Statements made in this press release that are not historical facts are forward-looking statements. Investors are cautioned that all forward-looking statements necessarily involve risks and uncertainties, and many factors could cause actual results and events to differ materially from those contemplated in the forward-looking statements. When we use any of the words believes, expects, anticipates or similar expressions, we are making forward-looking statements. The following factors, among others, could cause actual results and events to differ from those contemplated in the forward-looking statements: uncertainties associated with general or local economic conditions; changes in the interest rate environment or government monetary policy; inflation; political, legislative or regulatory developments; acts of war or terrorism; the markets acceptance of and demand for the Company s products and services; technological changes, including the impact of the internet on the Company s business and on the financial services market place generally; the impact of competitive products and pricing; and dependence on third party suppliers. For further information, please refer to the Company s reports filed with the Securities and Exchange Commission at www.sec.gov(link is external).
FacebookTwitterLinkedInEmailPrint分享Dave Mayfield for the Virginia Pilot:Virginia could see as many as 14,000 jobs in the offshore wind energy industry over the next 15 years, according to a report issued by a group called the American Jobs Project. The report, written in partnership with Virginia Tech and issued this month, said the state is particularly well positioned for the placement of offshore turbines.The report said the Hampton Roads port could become an East Coast hub for shipments of turbines and their components.Among the report’s recommendations are overseas trade trips specifically oriented to court companies in the wind industry and the revival of a regional East Coast alliance of states to jointly promote wind projects.Virginia is a laggard in wind power. But Dominion Virginia Power is considering whether to build two test turbines off the Virginia Beach coast, and it holds an adjacent lease that would allow it to develop a large commercial wind farm.The American Jobs Project report said Virginia also has the potential for as many as 5,000 jobs in carbon fiber composite materials over the next 15 years.Report eyes jobs in Virginia offshore wind industry 14,000 Jobs Seen in Virginia Offshore Wind Expansion by 2030